Most patients present to the doctor with ‘dyspepsia’ – a term that means so many things to different people that it needs some expansion: the majority of patients will not feel satisfaction when eating and many some upper abdominal discomfort or pain. Others will find fullness or discomfort such as leads their appetite to suffer. Others will find themselves full after a small amount of food or that the have lost the desire to eat. Weight loss ensues.
If the patient presents late then discomfort due to enlargement of the liver – due to spread of the cancer to this organ – may occur or jaundice due to liver dysfunction, for the same reason. This is clearly the most dangerous presentation.