Overall, this is a rare disease and a population based screening programme is not indicated.
However, if a patient is found (usually incidentally) to have a slightly raised level of a (monoclonal) immunoglobulin in the blood on some routine blood test (see monoclonal gammopathy of unknown significance below) then this individual requires to be followed carefully with repeat testing of the blood immunoglobulin levels over time, and further tests such as bone x-rays and bone marrow sampling if the levels rise.
