Overall, this is a rare disease and a population based screening programme is not indicated.
However, if a patient is found (usually incidentally) to have a slightly raised level of a (monoclonal) immunoglobulin in the blood on some routine blood test- see monoclonal gammopathy of unknown significance - below) then this individual requires to be followed carefully with repeat testing of the blood immunoglobulin levels over time, and further tests such as bone x-rays and bone marrow sampling if the levels rise.
