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| In patients with advanced thyroid cancer, radioactive iodine therapy can be very effective. However, there are some patients who fail to respond to this and the alternative options are... |
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| At the recent 2007 American Society of Clinical Oncology meeting in Chicago, data were presented of a clinical trial in which patients with advanced primary liver cancer (hepatocellular carcinoma)... |
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| In the last few years, there has been an increasing number of chemotherapy drugs that have shown usefulness in advancing prostate cancer (resistant to hormone therapies). Taxotere and mitozantrone... |
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| In a recent trial reported from Kentucky, thirteen out seventeen patients with differentiated (i.e papillary or follicular) thyroid cancer (76%) responded to thalidomide therapy. It is regarded that... |
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| One of the problems in the management of the patient with thyroid cancer, who is being followed up by both radio-iodine tracer whole body scanning and serial thyroglobulin levels in the serum, is that... |
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| Recent work has shown that the isotope I-123 is a better imaging agent than I-131 and mmost large thyroid cancer centres are moving over to this newer imaging agent for the scan detection of recurrent... |
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| Dr. M Ozsahin (Universitaire Vaudois, Switzerland) presesnted data on the follow-up of 37 patients with primary testicular lymphoma. This rare presentation of extranodal lymphoma tended to present... |
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| An epidemiological study from Japan has just been published (New Eng J Med 2001; 345: 784-9) strongly linking heliobacter infection with the development of stomach/gastric cancer. 1526 Japanese... |
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| Familial diffuse gastric cancer is an autosomally inherited disease that develops at a younger age than the much commoner sporadic form of this cancer. Germ line truncating mutations in the E-cadherin... |
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| Recently presented data from Duke University, North Carolina suggests that topoisomerase 1 inhibitors (specifically topotecan, irinotecan and 9-amino-camtothecin) have activity in in vitro glioma and... |
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| Gastrointestinal stromal tumours/sarcomas are characterised by the expression of c-kit proto-oncogene product (KIT) and tend to respond poorly to orthodox chemotherapy. ST1571, a signal transduction... |
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| This salvage chemotherapy regimen, devised for patients who had failed adriamycin (doxorubicin based chemotherapy) has been claimed to be the best supportive chemotherapy regimen around at present and... |
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| The routine use of chemotherapy after surgery for soft tissue sarcopmas is not established therapy. In an attempt to use the chemotherapy mopre successfully, several trials have looked at the use of... |
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| A European trial looking at a two drug adjuvant chemotherapy regimen (adriamycin and cis-platinum) versus the same drugs plus a third viz. methotrexate showed no advantage to adding the methotrexate... |
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| PET scanning, a new form of functional scanning, is good at telling not only whether the sarcoma has spread/metastasised, but also whether a sarcoma is of high grade (and hence likely to behave... |
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| Doxorubicin is the best established chemotherapy agent in sarcoma therapy. The relatively newly liposomal formulation of the compound has been shown to have similar activity against the cancer but a... |
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| As soft tissue sarcoma in children is a proven indication for adjuvant chemotherapy, so, if there is any group for whom a strategy of high dose chemotherapy (above marrow death – thus the need... |
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| The subject of who should receive post –operative chemotherapy for localised soft tissue sarcoma has been a controversial one for over a decade. The subject has been overviewed at the... |
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| In a randomised SWOG trial presented at the 47th meeting of the American Society for Therapeutic Radiology, 425 men with positive margins in the surgical resection specimen after radical... |
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| A recent study reported from California looked at the rise in the blood/serum PSAprior to surgery for early prostate cancer. The authors found where there was a rise of more than 2ng/ml/year the... |
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